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High-dose IM injections or nasal sprays are approved to rapidly correct severe deficiencies that have caused neurological damage
Any suspected adverse reactions to medicines can be reported through the MHRA Yellow Card scheme
Without an intrinsic factor, oral B12 cannot be absorbed
Remember that clinical trials failed to demonstrate statistically significant weight loss in the largest study, leading to development termination in 2007
Reconstitute with bacteriostatic (BAC) water for laboratory use, keep the reconstituted solution refrigerated, and use within a few weeks
The core formula is: Volume to draw (mL) = desired dose (mg) / concentration (mg/mL) Concentration comes from the vial and BAC water: Concentration (mg/mL) = total vial amount (mg) / BAC water added (mL) On a U-100 syringe, 1 mL equals 100 units
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