A., Swaika, A
Androgen receptors are expressed by murine and human macrophages, monocytes, neutrophils, T cells, and B cells, in which they exhibit predominantly anti-inflammatory and immunosuppressive effects ( In human monocyte-derived macrophages, murine peritoneal macrophages, and human and murine macrophage cell lines (e.g., RAW 264.7 and J774A.1), testosterone dose-dependently inhibited LPS-induced production of nitric oxide (NO) and TNF, as well as expression of inducible nitric oxide synthase (iNOS/ Nos2 ) and TLR4 (110115)
For immunolocalization, a rabbit anti-GSH (reduced) antibody (Agrisera, Vnns, Sweden) was diluted 1:100 in TBS (50 mM Tris-HCl, 150 mM NaCl, pH 7.5) containing 2 mg mL 1 BSA and 0.4 mg mL 1 BSA-C
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Cordycepin ameliorates diabetic nephropathy injury by activating the slc7a11/gpx4 pathway