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Scientific interest has also focused on its selectivity profile relative to non-selective GHSPs, making it a valuable tool compound for delineating GHSR-1a-specific signaling from off-target receptor effects

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

Due to its dual peptide composition, this blend is frequently referenced in experimental peptide research models

41 In addition, the specific knockout or ablation of INSR in livers prevents insulin suppression of hepatic glucose production (HGP), 42,43 suggesting a direct role for INSR in hepatic IR