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The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort
MASH affects around 14.9 million adults in the U.S., or roughly 6% of the population, and its prevalence is on the rise
Recent clinical data shows that GLP-1 receptor agonists like semaglutide can reduce cholesterol levels while promoting weight loss, offering a two-pronged approach to cardiovascular health
Since the FDA ruled theres no longer a shortage of semaglutide and tirzepatide, compound pharmacies increasingly rely on custom doses and formulations, such as mixing the medication with vitamins or using new pills or tinctures
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An additional study compared weight loss outcomes for semaglutide and tirzepatide but used data specifically for these medications labeled for T2DM and thus included a large (52%) proportion of patients with T2DM
Kumar et al 2017
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