Aside from hyperhomocysteinemia, C677T or A1298C MTHFR (the two genes most studied) mutations are associated with an increased risk of other conditions including cardiovascular and thromboembolic diseases such as strokes, blood clots, and heart attacks, ADHD in children, pregnancies with neural tube defects, depression, anxiety, diabetic neuropathy, glaucoma migraines, schizophrenia, and colorectal polyps
Chemotherapy patients: ALCAR significantly worsened chemotherapy-induced peripheral neuropathy in a placebo-controlled trial (Hershman et al
It also stimulates collagen and elastin synthesis through fibroblast activation, and its copper-chelating properties contribute to antioxidant defense by modulating copper-dependent superoxide dismutase activity
Recovery is not only about reducing pain
These statements have not been evaluated by the Food and Drug Administration, and these products are not intended to diagnose, treat, cure or prevent any disease.
Nogus et al