A series of 10 phase 3 multicenter, randomized clinical studies as part of the Peptide InnOvatioN for Early diabetes tReatment (PIONEER) program were conducted to compare the efficacy and safety of oral semaglutide with either placebo or active comparators [2131]
The concern is pancreatitis
Good Overall Health: Individuals should be in good overall health to undergo the procedure
Also avoid drinking large amounts of liquid with meals, as this can increase fullness and nausea
and, Additional risks to watch out for when taking Ozempic include thyroid C-cell tumors, other thyroid issues, pancreatitis, diabetic retinopathy, acute kidney injury, hypersensitivity, acute gallbladder disease, hypoglycemia (when used with insulin/sulfonylurea), injection site reactions, and allergic reactions
Many researchers attribute this to tolerance when the real culprit is a degraded vial