Tirzepatide, another GLP-1 option, was not included because it became available after the study began
Most of the research in this area has focused specifically on alcohol addiction, and researchers have known for a while now from animal studies that GLP-1 receptor agonists decrease alcohol intake, reduce the motivation to consume alcohol, and even prevent relapse drinking by potentially lowering alcohol-induced reward
239,240 In summary, GLP-1 lowers blood glucose levels and inhibits glucagon secretion through direct action on -cells, promotion of insulin secretion, and regulation of gastrointestinal activity
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In the current investigation, we found that osteoblastic ferroptosis constituted a pivotal factor contributing to the pathogenesis of PPO
npj Precision Oncol 2017 1(1 1):19