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Reported phase 1b and phase 2 data describe dose-ranging pharmacokinetic and pharmacodynamic profiles, while structural biology studies have begun to map its binding mode across the three class B GPCRs

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The following calculation was used: FoB cell sorting for confocal microscopy and TEM was performed by MACS pre-enrichment with B cell isolation kit (Miltenyi Biotech 130-090-862)

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