At the top of the list: berberine, a plant compound dubbed natural semaglutide. Several Redditors report dropping more than 25 pounds in just weeks after adding berberine to their supplement stack, claiming that their results are comparable to prescription diabetes drugs like Ozempic and Metformin Berberine can be found over-the-counter at most health food and supplement stores for around $15 to $40 per bottle
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Incretin hormones cause the body to produce insulin when eating sugar, called the incretin effect
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