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72 StanleyTLFeldpauschMNOhJBranchKLLeeHTorrianiMet al

Drug Targets 21 , 884900 (2022)

Koushik et al., 2023)

With regard to pregnancy, breastfeeding, or any serious condition only a healthcare professional can advise

Results Study Selection A total of 195 records were initially identified through database searches

185 Besides, other MTHFD2 inhibitors have been reported, including DS18561882 and LY345899 in a substrate-based manner, and treatments based on them decrease cellular NADPH/NADP + ratio, increase cellular ROS levels, and impair tumorigenesis and metastasis