Related Molecular Mechanisms of Glucagon-Like Peptide-1 Receptor Agonists in Osteoporosis Glucagon-Like Peptide-1 Receptor/cAMP/PI3K/AKT Signal Pathway The PI3K/AKT signaling pathway plays an important role in regulating proliferation, osteoblast differentiation and osteoclast differentiation, apoptosis (Figure 1)
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Some medications are approved for diabetes , some for obesity , and some for both
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Although GLP-1 receptor agonists are generally well tolerated in metabolic populations, they are associated with potential side effects such as gastrointestinal discomfort, nausea, and appetite changes