It can also help a person lose weight, although the Food and Drug Administration (FDA) has not approved it for this use
Glucagon-Like Peptide-1 Receptor Agonists Activate Rodent Thyroid C-Cells Causing Calcitonin Release and C-Cell Proliferation
Prebiotic fibers and polyphenols enhance pathways often discussed in GLP-1 microbiome science , especially through SCFA production and microbiome activity
Although these medications dont typically produce the rapid 1520% average weight loss seen with GLP-1s, they can still lead to clinically meaningful reductions of about 510% of body weight, which can improve blood pressure, blood sugar, and cholesterol levels
doi:10.1098/rsfs.2019.0092
Pre-existing gastrointestinal disorders, particularly functional dyspepsia or irritable bowel syndrome, appear to predispose patients to more pronounced GI symptoms