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Community oral doses (50-150 mg daily) are based on allometric scaling from mouse studies, oral bioavailability data, and several years of community trial and error
Therefore, riboflavin deficiency will lead to the downregulation of GSH and oxidative stress, which is the predominant cause for reduced osteogenic capacities of BMSCs and enhanced osteoclastic potentials of osteoclast precursors [54, 55], finally leading to net bone loss
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It protects cell structures and helps cells perform their daily tasks efficiently