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Rodrigues DGB, Coelho D de M, Sitta , Jacques CED, Hauschild T, Manfredini V, Bakkali A, Struys EA, Jakobs C, Wajner M (2017) Experimental evidence of oxidative stress in patients with l-2-hydroxyglutaric aciduria and that l-carnitine attenuates in vitro DNA damage caused by d-2- hydroxyglutaric and l-2-hydroxyglutaric acids

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The speakers highlight the unexpectedly favorable discontinuation data in the 4 mg arm, where discontinuation rates were reportedly lower than placebo

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It is widely studied in metabolic and endocrine research models to investigate glucose regulation, hormone signaling, and receptor-mediated cellular responses under controlled experimental conditions

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