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By modulating TRP availability, central KP flux, glutamatergic signalling, oxidative stress, HPA-axis activity, and neuroplasticity, the microbiome-immune-BBB axis emerges as a mechanistic bridge linking peripheral physiology to central mood regulation
Additionally, it should be noted that ROS is a general term but not some specific molecule (4648)
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Glutathione (GSH) is highly abundant in all cell compartments and is the major soluble antioxidant
