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Studies have shown [11]: Prevention of gastric lesions when co-administered with NSAIDs Healing of existing NSAID-induced damage Protection of both upper and lower GI tract Preservation of intestinal permeability This is particularly significant given that millions of people take NSAIDs regularly, often experiencing GI side effects

DOI: 10.1016/j.jtcme.2021.02.004, Alsahli, M

It points to the importance of diet

B12 is a cofactor for the enzyme that converts methylmalonyl-CoA to succinyl-CoA

[6]

Adding high-intensity exercise compounds this stress and increases the risk of muscle injury, excessive fatigue, and prolonged soreness