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Yes, with adjusted doses and regular monitoring

Because serum alanine aminotransferase (ALT) levels have been reported to predict the histological course of NASH and because strict control of ALT is required to prevent the progression of NASH [13], the primary outcome of this study was a change in ALT levels

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No correlation was found between LC concentration and HDRS-24 scores ( r = 0.135, P = 0.271)