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While peptides are generally well-tolerated, monitoring allows early detection of elevated IGF-1, insulin changes, liver enzyme shifts, or other markers that warrant protocol adjustment

Author contributions ZJ, TI, and HN designed research, performed experiments, analyzed data, and wrote the manuscript

CCK-8 assay Cell growth was measured using a CCK-8 kit (Sigma, St Louis, MO, USA) according to the instructions

As with any growth-factor therapy, clinical oversight is crucial to ensure balanced dosing and to avoid overstimulation of growth pathways

PT-141 (Bremelanotide): Focused on Sexual Function PT-141, known as Bremelanotide, is a melanocortin peptide researched for sexual dysfunction, including erectile dysfunction (ED) and low sexual desire

Competition from local distributors creates pricing pressure