[6] [4] In other cases particularly where weight loss is rapid or psychological stress is elevated the autonomic nervous system (specifically the sympathetic branch) may become more active
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This has made it an exciting candidate for long-term obesity management
Indeed, in clinical practice, metformin demonstrated a variety of beneficial effects on menstrual disorder, anovulation, androgen excess, insulin resistance, and cardiovascular risk, whereas its weight loss effect is often inconsistent and transient [21, 22]
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For most patients, the treatment is a combination toxin to address the muscle activity creating new lines, filler to address the established static lines