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En el ensayo cardiovascular SUSTAIN-6, semaglutida redujo MACE (muerte cardiovascular, infarto agudo de miocardio no fatal o ictus no fatal) vs placebo: HR 0,74 (IC 95% 0,580,95)

Zhao G et al

Understanding the link between type 2 diabetes mellitus and parkinson's disease: role of brain insulin resistance

This ratio is one of the most reliable biomarkers of cellular redox status, measurable by HPLC or enzymatic assay (Forman et al., Mol Aspects Med 2009)

Dihexa was administered intraperitoneally (i.p.) at 0.5 mg/kg in phosphate buffered saline (PBS) on alternate days, commencing 15 days post-surgery and continuing through day 48, with control animals receiving PBS alone

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