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Ozempic (semaglutide) is a type 2 diabetes treatment, and part of a popular class of similar medications, known as glucagon-like peptide-1 (GLP-1) receptor agonists, which also includes Mounjaro, Wegovy, Zepbound, Victoza, Trulicity and other
A small number of patients report mild reactions including nausea, slight discomfort at the injection site, or temporary tiredness
These medicines work by mimicking the action of the naturally occurring hormone GLP-1, which is released from the intestine in response to food intake
Immune cells called macrophages can infiltrate adipose tissue and drive further inflammatory processes that contribute to insulin resistance
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So this is a growing threat that I think needs to be monitored closely. If GLP-1s do become prohibited, athletes could theoretically apply for a therapeutic use exemption (TUE), which allows them to take a drug if it is treating a legitimate medical condition, and does not meaningfully enhance their performance
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