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It also supports nerve regeneration and reduces oxidative stress two mechanisms thought to underlie its benefits for diabetic neuropathy.48 Randomized trials have shown that taking 1,0002,000mg of ALCAR daily may help reduce pain, improve vibration perception, and enhance nerve conduction in people with diabetic neuropathy especially when treatment begins early.49 Vibration perception refers to the ability to sense low-frequency vibrations, such as those from tuning forks a key part of nerve function often tested in clinical exams to assess sensory loss in the feet and legs

Min SH, Yoon JH, Hahn S, Cho YM (2018) Efficacy and safety of combination therapy with an -glucosidase inhibitor and a dipeptidyl peptidase-4 inhibitor in patients with type 2 diabetes mellitus: a systematic review with meta-analysis

Going slow can be a powerful way to reduce nausea and other digestive side effects, which usually resolve as your body adjusts

Should you consult a doctor

The insurer was paying $1,000 or more per month for medications that the majority of recipients would abandon within months, often without achieving the weight loss or metabolic improvements that justified the expense in the first place