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Diabetologia 52:1730 Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

The latter group demonstrated that the identified ligands induced orexigenic (appetite stimulating) responses and thus named the peptides orexin A and orexin B

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Glutathione reductase, while crucial for long-term redox homeostasis, works more as a maintenance system that ensures continued recycling of glutathione

Jones, The Health Dividend of Glutathione, Natural Med

However, others may report sleep disturbances as a side effect