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Discontinuation due to adverse events ranged 3.811.6% across doses, compared with 4.9% for placebo the exact rate per individual dose was not disclosed in topline results

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Additionally, it is suggested that the beneficial effects of GLP-1RAs on systolic blood pressure may be due to improvements in direct or indirect vasorelaxation of vascular smooth muscle in the kidneys as well as via endothelial function and natriuresis [98]

Helicobacter pylori upregulates circPGD and promotes development of gastric cancer

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