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Effective contraception while on GLP-1s is important

The letter cites objectionable conditions regarding the companys mandated reporting of adverse events for its GLP-1 drugs

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Cardiovascular effects: Phase 2 trial data indicate that retatrutide was associated with modest increases in resting heart rate, consistent with observations seen with other GLP-1 receptor agonists

A 10 mg vial covers roughly 23 weeks at that dose