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The peptide sequence of [desHis2, Leu3, desGly10]-LH-RH ethylamide, [desHis2, d-Ala6, desGly10]-LH-RH ethylamide and [desHis2, Leu3, D-Ala6, desGly10]-LH-RH ethylamide caused an inhibition of LH-RH-induced release of LH and FSH in rats 17

For these members, the purpose of the 503A question was not to declare efficacy but to decide whether prescribers and pharmacists should have a lawful patient-specific option

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