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Chronotropic refers specifically to rate, meaning these drugs tend to speed up how fast the heart beats

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Los medicamentos basados en este principio como semaglutida y liraglutida han cobrado una relevancia sin precedentes en los ltimos aos gracias a su eficacia para tratar la diabetes tipo 2 y reducir significativamente el peso corporal

These newly synthesized compounds were tested for in-vitro DPP-4 inhibitory activity, with fair to moderate results compared to linagliptin as the reference standard