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A.BoslettJ.VaradharajS.De PascaliF.HemannC.DruhanL

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Inositols in Insulin Signaling and Glucose Metabolism. International journal of endocrinology vol

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An atlas of genetic correlations across human diseases and traits

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Stem Cells, 35 (6), 14461460

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Meta-analizler ok sayda aratrmadan toplanan bilgiler nda genel eilimin hangi tarafa doru olduunu grmek iin zel istatistiksel analizlerin yapld bir nevi "aratrmalarn aratrmas" niteliindeki almalardr ve bilimsel kant piramidinde en st basamakta yer almaktadr (ekil 2)

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Three different tests: Tendon outgrowth , how many cells grow out from a piece of tendon in the dish Wound healing assay , cells are grown as a monolayer, you make a scratch in it and observe how quickly it closes Cell survival , you add peroxide (oxidative stress, which normally kills cells) and observe how many survive What they found: Tenocytes grew faster and in a dose-dependent curve (the more BPC-157, the more growth) The scratch closed 1.8 faster at 1 g/ml BPC-157 Under oxidative stress, 22 % of cells survived without BPC-157, but 67 % with BPC-157 When they blocked the FAK enzyme, the effect disappeared mechanism confirmed Why it matters: This is not just a systemic effect via blood, BPC-157 directly modifies the biology of an individual cell

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