Key considerations include: Pre-existing mental health conditions may be exacerbated during weight loss Physiological changes accompanying weight loss may affect emotional stability Medication effects on gastric emptying may reduce absorption of oral medications, including oral contraceptives (requiring backup contraception after initiation and dose increases) Social and lifestyle changes during treatment create psychological stressors Clinicians should maintain awareness that mood changes during Zepbound therapy likely represent multifactorial phenomena rather than simple cause-and-effect relationships
Omega-3 fatty acids may reduce the risk of coronary heart disease
Digestive Issues: You may experience diarrhea, constipation, or stomach pain
Second authorization confirmed On May 1, 2026, Health Canada authorized a second generic semaglutide injection, with the agency stating it is currently reviewing seven other submissions for generic semaglutide by different companies
The Food and Drug Administration regulates dietary supplements under the Dietary Supplement Health and Education Act, or DSHEA
Other reta boosters also flag its alleged ability to reduce cravings for drugs and alcohol