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Importantly, these trials exhibited a high degree of heterogeneity in terms of the types of substances studied, patient characteristics, and treatment protocols, which posed significant challenges to drawing definitive conclusions

Inflammatory cytokines blunt GLP-1 receptor responsiveness and destabilize insulin signaling, contributing to metabolic relapse

Clinical trials showed that curcumin can attenuate proteinuria in patients with DKD and lupus nephritis (Khajehdehi et al., 2011

3.6.2) using the tidyverse, ggpubr, and ggplot2 package

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