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Eli Lilly, the pharmaceutical company that makes Zepbound, blames the lack of coverage on the stigma of obesity

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With DPP4 inhibitors as a comparator previously shown to have neutral effects on cognition [10, 11], the present study demonstrates that SGLT2 inhibitors may reduce dementia risk in adults with type 2 diabetes aged 60 years, but the association between the study GLP1 receptor agonists and dementia risk reduction is less certain

Some have a bit of research backing them up, but honestly, the jury's still out on whether many of these supplements do much of anything at all