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doi: 10.3389/fphys.2020.605908 39 ChangW

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Its pathophysiological characteristics mainly manifest as diffuse alveolar damage, increased pulmonary microvascular permeability, and refractory hypoxemia ( Despite the fact that the implementation of the new definition aids in early intervention, the ensuing clinical heterogeneity paradox presents immense challenges for precision treatment

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The caloric deficit also means reduced protein availability for tissue synthesis, reduced micronutrient availability, and potentially reduced copper delivery to the enzymatic systems that GHK-Cus carrier function bypasses