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In the IMPACT trial, pemvidutide achieved mean weight losses of 4.8% and 5.8% with 1.2 and 1.8 mg doses respectively at 24 weeks, compared to 0.5% with placebo, with weight loss curves showing no evidence of plateauing, suggesting continued benefit with longer treatment [49-51]

When to Seek Medical Advice About Persistent Tiredness Whilst mild fatigue during the initial weeks of GLP-1 therapy may be expected as the body adjusts, certain situations warrant prompt medical evaluation

Theres no rule for how long leg pain lasts, given that many different health conditions may be behind it

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Some gut plans also focus on antimicrobial balance