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These exacerbated inflammatory responses entail upregulation of the angiotensin-converting enzyme-2 (ACE2) receptor, to which the SARS-CoV-2 virus spike protein (S protein) binds, thereby gaining entry to host cells (11, 13)

10.1093/ajcn/71.3.701 44

Secondary endpoints: GSH concentrations in maternal and arterial and venous umbilical cord blood erythrocytes (by stratification based on treatment or degree of IPTB severity) and safety of antenatal NAC supplementation for mothers and infants Considering stratification for IPTB severity, median glutathione concentration in venous cord blood was similar in severe (median: 430 mol/L) and moderate (median: 402 mol/L) IPTB in the NAC arm ( P 1.0), whereas it was lower, however not significantly ( P 0.67), in severe (median: 391 mol/L) than moderate (median: 522 mol/L) IPTB group in the placebo arm (Supplemental Table S3)

Apart from its internal health benefits, glutathione is recognized for its skin-related advantages, particularly its ability to lighten the skin by reducing melanin production

Nuclear sphingolipid metabolism