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But more physiologic does not mean no oversight needed. It still warrants a clear rationale, appropriate bloodwork, and monitoring over time

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A particularly informative pharmacological example is provided by the diazepine derivative YL3147, a highly potent radical-trapping antioxidant that directly interrupts the chain-propagation phase of lipid peroxidation and confers robust protection in both acute and chronic murine models of doxorubicin-induced cardiomyopathy