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Body mass and plasma insulin concentrations were similarly increased in db/db saline and db/db GLP-1 mice compared with in wild-type mice (Supplemental Figures 1D and 1E)

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In a prospective evaluation, the albumin concentration 14 mg/L in a urine sample increased approximately threefold the risk of CV events (HR 3.25

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Continue hydrating, targeting 60-70 ounces by mid-afternoon