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TGR5-deficient mice, unlike wild-type mice, exhibited altered tight junction expression, increased intestinal permeability, and greater vulnerability to chemically-induced colitis, highlighting TGR5s role in preserving the intestinal barrier (Sorrentino et al., 2020)

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Establishing a strong understanding of CKM syndrome and how chronic diseases can interact with one another can help propel healthcare to focus on a broader, holistic approach to care, including across kidney care

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Indications and Usage: Methylcobalamin, Folic Acid, Niacinamide Injection is indicated for the treatment of vitamin deficiencies, including vitamin B12 deficiency, folate deficiency, and niacin deficiency