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FIGURE 7 However, another peptide, codenamed SR18 (H-Igl-E-Aib-TFTSDLSDHYESKA-CONH 2 ), which contained several amino acids similar to those found on the GLP-1 and demonstrated a docking orientation similar to the GLP-1 with a binding energy score of 272.14, was rationally shortlisted for further studies as a first-generation GLP-1RA over the top-ranked peptide (H-Igl-E-Aib-AWMTSIISTMWAKH-CONH 2 )
However, this effectiveness comes with an exorbitant cost, with the retail price of these medications over $1000 per month [36] [37]
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Respuesta: La berberina se ha estudiado ampliamente por sus efectos positivos en resistencia a la insulina y control de glucosa, hacindola popular para prediabetes
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