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As B12 is a water-soluble vitamin, it's generally considered safe (because any not used will be excreted via your urine), but even so you shouldn't take more than the recommended doses unless recommended to do so by your GP, as some studies have shown possible negative impacts of overdoing it
Omega-3 fatty acids have modest but consistent evidence for supporting mood
You may also be able to try out red light therapy at a local wellness center, like Restore Hyper Wellness
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Metformin and Its Benefits for Various Diseases
Contraindications must also be assessed carefully to ensure safety: Known allergies to ingredients (especially sulfa-containing methionine)
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