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Unlike fat-soluble vitamins (A, D, E, and K) that can build up, B12 has a strong safety record and toxicity is rare
10.1016/j.curtheres.2014.01.001 58 Tuba-KartalA.ala-MutluZ
The storage is used when the delivery of the vitamin is poor
The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)
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For instance, Vitamin B12 is known to support cardiovascular health by reducing levels of homocysteine, an amino acid linked to heart disease
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