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Below GLP-1s, below approved oral pharmacotherapy, below surgery for appropriate candidates and beside, not instead of, diet and exercise
Patients taking Mounjaro with antidepressants should seek medical advice if they experience severe or persistent side effects that interfere with daily activities or medication adherence
One of their primary effects is slowing gastric emptying, meaning food stays in the stomach longer than usual
One current study reported that the inhibition of 5-HT release attenuates the activation of GLP-1 receptor signaling and highlighted the relationship between GLP-1 and 5-HT serotonin system (Anderberg et al., Another study mentioned that GLP-1 receptor agonist liraglutide could reduce the expression of 5-HT2A receptor and subsequently reduces body weight and inhibits serotonin synthesis in mice model (Nonogaki and Kaji, 2018)
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