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Additionally, factors such as UV radiation and aging exacerbate mtDNA damage, leading to diseases, particularly ocular conditions like dry eye and age-related macular disease (AMD) [82,83,84]

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In a separate 2 year double blinded, placebo-controlled study, weekly subcutaneous injections of semaglutide (2.4mg) in obese patients, average body weights decreased 12.6% over placebo at the 2-year point [23]

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