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It is important to note that these mechanistic effects are still being characterised in human studies, and the relative contribution of each receptor pathway to the drug's overall effects remains under investigation
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The two primary incretin hormones are: GLP-1 (glucagon-like peptide-1) GIP (glucose-dependent insulinotropic polypeptide) These hormones support metabolic balance by stimulating insulin secretion, inhibiting glucagon release (which would otherwise raise blood sugar), slowing gastric emptying (to help regulate the pace of digestion), and promoting a feeling of fullness or satiety, which can reduce overall food intake
Medicines in this class are now indicated for chronic weight management, obstructive sleep apnea, metabolic dysfunction-associated steatohepatitis, and other conditions
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Fourth, they are fast
