Clinical Trial Insights In SURMOUNT-1 and SURPASS trials, Mounjaro showed: Up to 22.5% body weight reduction in non-diabetic obese patients Greater HbA1c reductions vs Ozempic and insulin in diabetics Reference : Tirzepatide as Compared with Semaglutide for the Treatment of Obesity Reference : mounjaro.lilly.com/hcp/a1c-weight FDA approved Mounjaro for Type 2 Diabetes in 2022, and later for weight loss under the brand Zepbound in Nov 2023 (US)
Side effects like nausea, vomiting, and gastrointestinal discomfort are common
The recommended daily intake in the UK is 1.5 micrograms for adults , according to NHS guidance
Research progress of extracellular vesicles and exosomes derived from mesenchymal stem cells in the treatment of oxidative stress-related diseases
Anti-Oxidants: Resveratrol (Polygonum cuspidatum, root, 98 %) 5 mg,L-glutathione reduced 4 mg, Co-enzyme Q10 (Ubiquinone) 2 mg
These drugs aim to improve the oral bioavailability of peptides or use oral small molecules to further enhance patient adherence