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Drugs 78(11):11131132 dAquino AI, Maikawa CL, Nguyen LT, Lu K, Hall IA, Jons CK, et al (2023) Use of a biomimetic hydrogel depot technology for sustained delivery of GLP-1 receptor agonists reduces burden of diabetes management
It mainly affects debilitated, immunocompromised individuals
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Nonetheless, there remains an ongoing need for additional medicines, particularly those with a distinct mode of action that could be used independently or in combination with the current incretin-based therapeutics
GLP-1 treatments are especially beneficial for individuals managing type 2 diabetes and for women experiencing hormonal changes, such as menopause
investigated the effects of GLP-1(9-36), a metabolite produced by N- terminal dipeptide cleavage of native GLP-1(7-36), which exhibits very low affinity for the GLP-1-receptor, in comparison to GLP-1(7-36) and liraglutide
