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Korponay-Szab, I
Age-related cohesion loss around centromeres, a significant contributor to errors in chromosome segregation, is exacerbated by ROS-induced oxidation and carbonylation of proteins essential for spindle formation and stability, thereby increasing the risk of aneuploidy in offspring [4, 38]
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While the above evidence indicates that the mitochondrial apoptotic pathway promotes cell death, recent provocative evidence has shown that the intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in Caenorhabditis elegans by triggering a unique pattern of gene expression that modulates stress sensitivity and promotes survival (Yee et al., 2014)
5mg per vial Primary Benefits Activates tissue remodeling genes and enhances collagen production
PMID 10607817
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