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Thats telling us that there is likely a common biologic pathway that is driving all of these addictions that is indeed druggable or treatable by GLP-1. The proteins on brain cells that receive chemical signals from GLP-1 drugs, known as GLP-1 receptors, are found in an area called the mesolimbic system that is responsible for motivation and reward signaling, Al-Aly noted

Blood markers may change before nerve symptoms improve, and long-standing neurologic symptoms may take longer to assess

Evidence Summary Current evidence supports the following conclusions: GLP-1 drugs reduce caloric intake Reduced intake may reduce micronutrient consumption Delayed gastric emptying does not equal malabsorption Rapid weight loss may increase lean mass vulnerability Long-term micronutrient outcome data remain limited There is mechanistic plausibility for nutritional risk in certain populations, but no strong evidence of universal depletion across all patients

[17] Papp LV, Lu J, Holmgren A, Khanna KK

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They also have lower glutathione levels