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Both forms of D-2-HGA can trigger neonatal or early childhood epileptic encephalopathy, with hypotonia, developmental delay, seizures, and even cardiomyopathy, although D-2-HGA type II is usually more severe [8, 110]
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Related links cBioPortal: Glossary Acral melanomas Skin melanomas that form in non-glabrous skin such as the palms, soles or under fingernails or toenails and are the predominant form of melanoma in highly pigmented ethnicities
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Copper is also used in superoxide dismutase, an enzyme that handles oxidative stress, and oxidative stress is one driver of fine lines and dull tone after years of UV exposure
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