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Originally designed to treat obesity issues in HIV/AIDS patients, the peptide has since been shown to effectively treat growth hormone deficiency, improve sleep quality, and promote longevity, and is classified as a prohibited substance under Section S2 of the World Anti-Doping Agencys (WADA) Prohibited List [2, 3]
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OASIS investigators found that in the treatment-policy estimand, adults who received oral semaglutide lost 15.1% of their body weight at 68 weeks compared with a 2.4% weight loss for placebo (estimated treatment difference -12.7 percentage points, 95% CI -14.2 to -11.3
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