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[PMID: 15639858] PubMed record related to this compound for laboratory literature review
The oral SEMA formulation was approved by the FDA as an adjunct to diet and exercise to improve glycemic control in adults with T2DM
When activated, the mast cells in the skin release mediators (histamines, tryptase, TNF-alpha, CXCL9, etc.) that cause inflammation, flushing, itching, or burning.[ref] Related article: Rosacea, underlying causes, genetic susceptibility Dermatographism and mast cell activation syndrome: In a survey of mast cell activation syndrome, dermatographism was found in 89% of the patients.[ref] Dermatographism is when you get welts or raised red lines when you scratch your skin lightly
Gynecol Endocrinol 2019;35(8):701-5
Some people taking GLP-1s experience side effects, including: Nausea Changes in appetite Digestive sensitivity to rich or unfamiliar foods Travel itself new foods, dehydration, irregular meals can sometimes amplify these side effects